TIMP-2 Protein, Human
SKU: 20338721178

TIMP-2 Protein, Human

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Description

TIMP-2 Protein, HumanProduct Specification Species Human Synonyms CSC 21K,TIMP2 Accession P16035 Amino Acid Sequence Cys27 Pro220, with C terminal His Tag Expression System HEK293 Molecular Weight 22 24 kDa (Reducing) Purity 95% by SDS PAGE and HPLC. Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, 5% trehalose, PH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water

Product Specification


Species Human
Synonyms CSC-21K,TIMP2
Accession P16035
Amino Acid Sequence Cys27-Pro220, with C-terminal His Tag
Expression System HEK293
Molecular Weight

22-24 kDa (Reducing)

Purity >95% by SDS-PAGE and HPLC.
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, 5% trehalose, PH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Sci Rep . 2021 Jan 13;11(1):1071.

Background

TIMP metallopeptidase inhibitor 2 is also known as TIMP2, which belongs to the protease inhibitor I35 (TIMP) family. The total length of TIMP-2 Protein, Human (HEK293, His) is 194 a.a., with molecular weight of 22-24 kDa. TIMP-2 protein is a tissue inhibitor of metalloproteinases that can bind and inactivate various metalloproteinases, including collagenases, such as MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9 , MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. TIMP2 is a 22 kDa non N-glycosylated protein expressed by a variety of cell types, and plays a unique role among TIMP family members owing to its functions to regulate cellular responses to growth factors.

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SKU: 20338721178

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