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Description
FITC Mouse Anti-Human CD2 Antibody (S-633-25)Product Specification Host Mouse Antigen CD2 Synonyms T cell surface antigen CD2; Erythrocyte receptor; LFA 2; LFA 3 receptor; Rosette receptor; T cell surface antigen T11 Leu 5; SRBC Immunogen Recombinant Protein Location Cell membrane Accession P06729 Clone Number S 633 25 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human Peripheral Blood cells Purification Protein G Concentration 0. 05mg ml Conjugation FITC
Product Specification
| Host | Mouse |
| Antigen | CD2 |
| Synonyms | T-cell surface antigen CD2; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; SRBC |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | P06729 |
| Clone Number | S-633-25 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human Peripheral Blood cells |
| Purification | Protein G |
| Concentration | 0.05mg/ml |
| Conjugation | FITC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD2, also known as the T-cell surface antigen CD2, is a transmembrane glycoprotein primarily expressed on the surface of T cells and natural killer (NK) cells. It belongs to the immunoglobulin superfamily and plays a crucial role in mediating cell adhesion and activation. CD2's principal ligand is CD58 (LFA-3), which is expressed on antigen-presenting cells and other immune cells. The interaction between CD2 and CD58 facilitates T-cell activation and enhances the immune response. Structurally, CD2 consists of an extracellular domain responsible for ligand binding, a transmembrane domain anchoring it to the cell membrane, and an intracellular domain involved in signal transduction.
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Exchange/Return Notes
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