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Description
CD42a Recombinant Rabbit mAb (S-2705-46)Product Specification Host Rabbit Antigen CD42a Synonyms Platelet glycoprotein IX; GP IX; GPIX; Glycoprotein 9; GP9 Immunogen Recombinant Protein Location Membrane Accession P14770 Clone Number S 2705 46 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IF Reactivity Hu, Ms Positive Sample Human spleen, mouse plasma, mouse spleen Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage
Product Specification
| Host | Rabbit |
| Antigen | CD42a |
| Synonyms | Platelet glycoprotein IX; GP-IX; GPIX; Glycoprotein 9; GP9 |
| Immunogen | Recombinant Protein |
| Location | Membrane |
| Accession | P14770 |
| Clone Number | S-2705-46 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IF |
| Reactivity | Hu, Ms |
| Positive Sample | Human spleen, mouse plasma, mouse spleen |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500-1:1000 | Hu, Ms |
| IHC-P | 1:500 | Hu, Ms |
| IF | 1:500 | Hu |
Background
CD42a, also known as glycoprotein IX (GPIX), is a small, single-pass transmembrane glycoprotein expressed on platelets and megakaryocytes that non-covalently associates with glycoproteins Ibα, Ibβ, and V to form the GPIb-V-IX complex, which acts as the platelet receptor for von Willebrand factor (vWF), enabling vWF-dependent platelet adhesion to injured vessel walls and initiating arterial hemostasis; CD42a contains leucine-rich repeats, is encoded by GP9 on chromosome 3q21.3, and mutations in this gene cause Bernard–Soulier syndrome, a bleeding disorder characterized by giant platelets and impaired aggregation.
Shipping Notes
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
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