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Description
Phospho-Glycogen Synthase (Ser641) Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen Phospho Glycogen Synthase (Ser641) Synonyms Glycogen [starch] synthase, muscle; Glycogen synthase 1; GYS; GYS1 Immunogen Synthetic Peptide Location Cytoplasm Accession P13807 Antibody Type Polyclonal antibody Isotype IgG Application WB Reactivity Hu, Ms, Rt Positive Sample HeLa, NIH 3T3, PC 12 Purification Immunogen Affinity Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage
Product Specification
| Host | Rabbit |
| Antigen | Phospho-Glycogen Synthase (Ser641) |
| Synonyms | Glycogen [starch] synthase, muscle; Glycogen synthase 1; GYS; GYS1 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | P13807 |
| Antibody Type | Polyclonal antibody |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | HeLa, NIH/3T3, PC-12 |
| Purification | Immunogen Affinity |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| Dot Blot | 1:1000 | |
| WB | 1:500-1:1000 | Hu, Ms, Rt |
Background
Phospho-Glycogen Synthase (Ser641) is the inactive, phosphorylated form of glycogen synthase in which a phosphate group is covalently attached to serine-641; this single modification, catalyzed chiefly by glycogen synthase kinase-3 (GSK-3) downstream of insulin signaling, sterically hinders the enzyme’s active site and prevents the elongation of glycogen chains, thereby providing a rapid, reversible switch that links hormonal cues to systemic glucose storage.
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